rsalazar Posted March 21, 2020 Hard to believe, but the act of humming cranks up nitric oxide production in the sinuses - nitric oxide is a part of the local defenses used against bacteria and viruses, nitric oxide is broadly antimicrobial - It seems the optimal humming is whatever range vibrates your nose and sinuses the most - also interesting that there is one case study of a patient with chronic sinusitis that cleared it over 4 days of extensive humming 1-2 hours a day - perhaps a great time to get some OM in the day  Am J Respir Crit Care Med, 166 (2), 144-5 2002 Jul 15 Humming Greatly Increases Nasal Nitric Oxide Eddie Weitzberg 1, Jon O N Lundberg Affiliations expand PMID: 12119224 DOI: 10.1164/rccm.200202-138BC Abstract The paranasal sinuses are major producers of nitric oxide (NO). We hypothesized that oscillating airflow produced by humming would enhance sinus ventilation and thereby increase nasal NO levels. Ten healthy subjects took part in the study. Nasal NO was measured with a chemiluminescence technique during humming and quiet single-breath exhalations at a fixed flow rate. NO increased 15-fold during humming compared with quiet exhalation. In a two-compartment model of the nose and sinus, oscillating airflow caused a dramatic increase in gas exchange between the cavities. Obstruction of the sinus ostium is a central event in the pathogenesis of sinusitis. Nasal NO measurements during humming may be a useful noninvasive test of sinus NO production and ostial patency. In addition, any therapeutic effects of the improved sinus ventilation caused by humming should be investigated. 4 1 Share this post Link to post Share on other sites